Journal article

A trajectory-based approach to understand the factors associated with persistent depressive symptoms in primary care

J Gunn, P Elliott, K Densley, A Middleton, G Ambresin, C Dowrick, H Herrman, K Hegarty, G Gilchrist, F Griffiths

Journal of Affective Disorders | ELSEVIER | Published : 2013

Abstract

Background: Depression screening in primary care yields high numbers. Knowledge of how depressive symptoms change over time is limited, making decisions about type, intensity, frequency and length of treatment and follow-up difficult. This study is aimed to identify depressive symptom trajectories and associated socio-demographic, co-morbidity, health service use and treatment factors to inform clinical care. Methods: 789 people scoring 16 or more on the CES-D recruited from 30 randomly selected Australian family practices. Depressive symptoms are measured using PHQ-9 at 3, 6, 9 and 12 months. Results: Growth mixture modelling identified a five-class trajectory model as the best fitting (low..

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Grants

Awarded by Australian Primary Health Care Research Institute, Australian National University


Funding Acknowledgements

The diamond study was initiated with pilot funding from the beyondblue Victorian Centre of Excellence and the main cohort has received project grant funding from the Australian National Health and Medical Research Council (IDs 299869, 454463, 566511 and 1002908). The one year Computer Assisted Telephone Interview was funded by a Stream 3 grant from the Australian Primary Health Care Research Institute (APHCRI). No funding body had a role in study design; the collection, analysis, and interpretation of data; the writing of the manuscript; or the decision to submit this manuscript for publication.